Knowledge Products

The ocean and its resources are the lifelines of Asia and the Pacific. As a resource for the economy, livelihoods and identity for coastal communities, the condition of the ocean is inextricably linked to the pathways of sustainable development in Asia and the Pacific. Produced in line with the 76th Session of the Economic and [...]

African countries are using technology in many new ways to fight the coronavirus pandemic. This report highlights some of the best digital solutions and estimates the investments required to implement the technology on a wider scale. This paper is intended to contribute to the European Union’s response to the coronavirus. This joint EU response includes [...]

This Trade and Development Report Update by the UN Conference on Trade and Development (UNCTAD) discusses how developing countries can build solidarity to weather the interconnected economic and public health crises. The report titled, ‘South-South Cooperation at the Time of COVID-19,’ highlights “North-South divergence” in combating the pandemic. UNCTAD points to developing countries as being [...]

By Brendan Vickers & Salamat Ali, Commonwealth Secretariat The COVID-19 pandemic is an unprecedented health, economic and humanitarian crisis for the world’s 47 least developed countries (LDCs), including 14 Commonwealth member countries in Africa, Asia and the Pacific. This issue of Trade Hot Topics analyses the trade flows in medical goods that matter for the [...]

COVID-19 has affected men and women differently. Although more men have died from the pandemic, women’s mental health is taking a bigger toll, their workload at home has multiplied and their economic resources are dwindling. These effects are hard to capture, as social distancing measures have rendered traditional data collection methods impossible. In response to [...]

The latest edition of the State of Food Security and Nutrition in the World, published today, estimates that almost 690 million people went hungry in 2019 – up by 10 million from 2018, and by nearly 60 million in five years. High costs and low affordability also mean billions cannot eat healthily or nutritiously. The [...]

The Human Papillomavirus E7 oncoprotein plays an essential role in the development and maintenance of malignancy, which it achieves through targeting a number of critical cell con- trol pathways. An important element in the ability of E7 to contribute towards cell transforma- tion is the presence of a Casein Kinase II phospho-acceptor site within the [...]

Anti-tuberculosis (TB) drugs, while being highly potent in vitro, require prolonged treatment to control Mycobacterium tuberculosis (Mtb) infections in vivo. This research article reports here that mesenchymal stem cells (MSCs) shelter Mtb to help tolerate anti-TB drugs. MSCs readily take up Mtb and allow unabated mycobacterial growth despite having a functional innate pathway of phagosome [...]

The innate response to a pathogen is critical in determining the outcome of the infection. However, the interplay of different cellular responses that are activated following viral infection and their contribution to innate antiviral signalling has not been clearly established. This work shows that flaviviruses, including Dengue, Zika, West Nile and Tick-borne encephalitis viruses, activate [...]

In 2019, over 600 scientists representing more than 47 nationalities were on board in the ICGEB laboratories, undertaking research across five macro-areas (Infectious Diseases, Non- Communicable Diseases, Medical Biotechnology, Industrial Biotechnology, and Plant Biology and Biotechnology). In Trieste, 18 Research Groups, comprising over 170 researchers have been active in various fields of biomedical research, including [...]